diff --git a/.github/workflows/publish_binary.yml b/.github/workflows/publish_binary.yml
index c3ce5fbb..d958c217 100644
--- a/.github/workflows/publish_binary.yml
+++ b/.github/workflows/publish_binary.yml
@@ -7,26 +7,42 @@ on:
         description: A CPython version accepted by `pyenv install`
         required: true
         type: string
+      platform:
+        description: Platform to build on
+        required: true
+        type: choice
+        default: ubuntu-24.04
+        options:
+          - ubuntu-24.04
+          - macos-15
 
 permissions:
   contents: read
 
 jobs:
-  publish_ubuntu:
-    runs-on: ubuntu-24.04
+  publish:
+    runs-on: ${{ inputs.platform }}
     env:
       PYENV_ROOT: ${{ github.workspace }}
       VERSION: ${{ inputs.version }}
     steps:
       - uses: actions/checkout@v7
-      - name: Install build prerequisites
+      - name: Install Ubuntu build prerequisites
+        if: runner.os == 'Linux'
         run: ./bin/pyenv install-prerequisites
+      - name: Install macOS build prerequisites
+        if: runner.os == 'macOS'
+        run: brew install openssl readline sqlite3 xz tcl-tk@8 libb2 zstd
       - name: Build package
         env:
           PYTHON_CONFIGURE_OPTS: --enable-optimizations
         run: |
           VERSION="${VERSION%%:*}"
-          entry="$(./bin/pyenv binary package-name "$VERSION")"
+          if [ "$RUNNER_OS" = "macOS" ]; then
+            entry="${VERSION}-${{ inputs.platform }}-$(uname -m)"
+          else
+            entry="$(./bin/pyenv binary package-name "$VERSION")"
+          fi
           echo "entry=$entry" >> "$GITHUB_ENV"
           mkdir dist
           cd dist
diff --git a/plugins/pyenv-binary/libexec/pyenv-binary-relocate b/plugins/pyenv-binary/libexec/pyenv-binary-relocate
index d73f682d..1620f325 100755
--- a/plugins/pyenv-binary/libexec/pyenv-binary-relocate
+++ b/plugins/pyenv-binary/libexec/pyenv-binary-relocate
@@ -100,6 +100,22 @@ if [ "$(uname -s)" = "Darwin" ]; then
   while IFS= read -r so; do
     relocate_macho "$so" '@loader_path/../..'
   done < <(find "$prefix" -type f -path '*/lib/python*/lib-dynload/*.so')
+
+  # CPython records its installation prefix in generated scripts and build
+  # metadata. Bytecode can also retain source filenames from the build tree.
+  build_prefix_pattern="$(printf '%s\n' "$build_prefix" | sed 's/[][\\.^$*|]/\\&/g')"
+  prefix_replacement="$(printf '%s\n' "$prefix" | sed 's/[\\&|]/\\&/g')"
+  while IFS= read -r file; do
+    if LC_ALL=C grep -IqF "$build_prefix" "$file"; then
+      sed -i.bak "s|${build_prefix_pattern}|${prefix_replacement}|g" "$file"
+      rm -f "${file}.bak"
+    fi
+  done < <(find "$prefix" -type f ! -name '*.pyc' ! -name '*.pyo')
+  while IFS= read -r file; do
+    if LC_ALL=C grep -aqF "$build_prefix" "$file"; then
+      rm -f "$file"
+    fi
+  done < <(find "$prefix" -type f \( -name '*.pyc' -o -name '*.pyo' \))
   exit
 fi
 
diff --git a/plugins/pyenv-binary/test/relocate.bats b/plugins/pyenv-binary/test/relocate.bats
index e14700b7..fa1bcb4f 100644
--- a/plugins/pyenv-binary/test/relocate.bats
+++ b/plugins/pyenv-binary/test/relocate.bats
@@ -23,11 +23,25 @@ create_interpreter() {
 }
 
 create_macos_tree() {
-  local prefix="${BATS_TEST_TMPDIR}/prefix"
+  local prefix="${BATS_TEST_TMPDIR}/prefix&target"
   local lib="${prefix}/lib/python3.12"
-  mkdir -p "${prefix}/bin" "${lib}/lib-dynload" "${lib}/site-packages/numpy"
+  local old="/build prefix/3.12.7"
+  mkdir -p \
+    "${prefix}/bin" \
+    "${prefix}/lib/pkgconfig" \
+    "${lib}/__pycache__" \
+    "${lib}/lib-dynload" \
+    "${lib}/site-packages/numpy"
   printf '#!/bin/sh\n' > "${prefix}/bin/python3.12"
   chmod +x "${prefix}/bin/python3.12"
+  printf '#!%s/bin/python3.12\n' "$old" > "${prefix}/bin/pip3"
+  chmod +x "${prefix}/bin/pip3"
+  printf 'prefix=%s\n' "$old" > "${prefix}/lib/pkgconfig/python-3.12.pc"
+  printf 'prefix=/build prefix/3x12x7\n' > "${prefix}/lib/pkgconfig/unrelated.pc"
+  printf 'prefix = "%s"\n' "$old" > "${lib}/_sysconfigdata.py"
+  printf '\0bytecode:%s/module.py\n' "$old" > "${lib}/__pycache__/module.cpython-312.pyc"
+  printf '\0bytecode:%s/legacy.py\n' "$old" > "${lib}/legacy.pyo"
+  printf '\0sourceless bytecode\n' > "${lib}/sourceless.pyc"
   touch "${prefix}/lib/libpython3.12.dylib"
   touch "${lib}/lib-dynload/_ssl.cpython-312-darwin.so"
   touch "${lib}/site-packages/numpy/_multiarray.so"
@@ -45,6 +59,9 @@ case "$1" in
 -L )
   echo "${file}:"
   case "$file" in
+  */bin/pip3 )
+    exit 1
+    ;;
   */bin/python3.12 )
     if [ -n "$OTOOL_RELOCATED" ]; then
       echo "    @rpath/libpython3.12.dylib (compatibility version 3.12.0, current version 3.12.0)"
@@ -179,7 +196,7 @@ STUB
 }
 
 @test "relocates macOS load commands without changing unrelated entries" {
-  local prefix="${BATS_TEST_TMPDIR}/prefix"
+  local prefix="${BATS_TEST_TMPDIR}/prefix&target"
   local old="/build prefix/3.12.7"
   local lib="${prefix}/lib/python3.12"
   create_macos_tree
@@ -197,10 +214,21 @@ STUB
 EOF
   run grep -F "${lib}/site-packages/numpy/_multiarray.so" "${BATS_TEST_TMPDIR}/otool.log"
   assert_failure
+  run head -n 1 "${prefix}/bin/pip3"
+  assert_output "#!${prefix}/bin/python3.12"
+  run cat "${prefix}/lib/pkgconfig/python-3.12.pc"
+  assert_output "prefix=${prefix}"
+  run cat "${prefix}/lib/pkgconfig/unrelated.pc"
+  assert_output "prefix=/build prefix/3x12x7"
+  run cat "${lib}/_sysconfigdata.py"
+  assert_output "prefix = \"${prefix}\""
+  assert [ ! -e "${lib}/__pycache__/module.cpython-312.pyc" ]
+  assert [ ! -e "${lib}/legacy.pyo" ]
+  assert [ -e "${lib}/sourceless.pyc" ]
 }
 
 @test "skips already relocated macOS load commands" {
-  local prefix="${BATS_TEST_TMPDIR}/prefix"
+  local prefix="${BATS_TEST_TMPDIR}/prefix&target"
   create_macos_tree
   stub_macos_tools
   export OTOOL_RELOCATED=1
@@ -211,7 +239,7 @@ EOF
 }
 
 @test "fails when install_name_tool cannot modify a selected file" {
-  local prefix="${BATS_TEST_TMPDIR}/prefix"
+  local prefix="${BATS_TEST_TMPDIR}/prefix&target"
   create_macos_tree
   stub_macos_tools
   create_path_executable install_name_tool 'exit 1'